Transcription factors have long been considered undruggable despite their central role in disease. New therapeutic modalities are finally changing that equation, bringing fresh hope to targeting these master regulators of gene expression.
Researchers have successfully developed gene-edited pigs that demonstrate complete immunity to classical swine fever, a major viral disease affecting global pork production. The breakthrough could significantly improve animal welfare while reducing economic losses and environmental impacts. The same genetic approach may also protect cattle and sheep from related viral diseases.
Scientists have reportedly created gene-edited pigs that show complete resistance to classical swine fever, a highly contagious viral disease that has plagued pig farmers worldwide for decades. According to research findings, a single tiny genetic modification effectively blocks the virus’s ability to replicate within the animals, preventing infection while maintaining normal health and behavior.
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